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agents. The exact mechanism by which these agents stop viral infections is still uncertain, but it is thought that incorporation in DNA or RNA may play a role. A series of now widely used antiviral drugs have come from a modi cation in which the ve-membered sugar is replaced by an open-chain equivalent. That portion of the molecule is depicted in the representatives in Figure 4 in admittedly tortured form to show the relation between the natural and open forms. The rst of these compounds acyclovir, came from a long-standing program at the Burroughs Wellcome Labs on modi ed nucleosides and nucleotides. This compound in essence opens the ring by omitting one carbon atom and the oxygen atom thereon. The actual synthesis of course involves a quite different route.7 The drug is active against a range of herpes viruses and is indicated for cold sores, shingles, and genital herpes. It is also useful for treating chicken pox as a result of its activity against the varicella virus. The later analog ganciclovir8 restores to the sugar surrogate one of the hydroxyl groups present in the natural nucleoside. Ganciclovir is indicated for treating cytomegalovirus retinitis. The fused two-ring purine fragment in each of the two preceding agents is hooked to the side chain via a carbon atom

The dissemination of policies (and, in general, the dissemination of any data) in a reliable and survivable fashion in a mobile ad hoc network poses special problems Although reliability of delivery can be provided by the use of a reliable transport protocol such as TCP or its MANET-appropriate variants,1 survivability is a challenge that cannot be addressed by TCP Survivability means the following: A survivable dissemination mechanism ensures that every node in the network to which data has to be disseminated will eventually receive the data, provided that it eventually becomes reachable Survivability is usually not of concern in highly reliable, static wireline networks; however, in MANETs where nodes typically have intermittent connectivity and may be disconnected from the network for long periods of time, survivability of dissemination of critical data such as policies for network management becomes a key requirement.

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Note that a reliable transport protocol such as TCP does not provide this survivability guarantee; indeed, all that such protocols guarantee is that either the data will reach its destination or the sender of the data will be informed about failure to deliver the data A survivable mechanism, however, must guarantee eventual delivery, even in the face of intermittent disconnection..

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Although elds and dimensions are similar, there are some distinct differences. All elds are dimensions, but not all dimensions are elds. Fields are created only from the data in the __utm.gif request. Dimensions are created from all the elds as well as using information that is calculated during the data processing. We explain elds and how they are used in lters in 5, and we cover dimensions and their application in 7. Once elds and dimension have been created, Google starts to apply the con guration settings to the data. Google Analytics begins by processing site search information. (See 5 for more information about con guring site search.) Next, Google applies lters to the data to modify the data. And nally, it applies pro le settings to the data. All these settings work together to modify the data in a Google Analytics Pro le; we explain each setting in 5. After the con guration settings have been applied, Google Analytics stores the processed data in a report database. Once the data has been stored, it can never be changed. This is an important point that we want to reiterate: Once the data has been processed and stored in the reporting database, it can never

As discussed earlier, access control policies are those that are used by a PDP to provide yes/no decisions in response to PEP requests. The most common example of such policies is authorization policies, which control access to resources. It should be noted that there are cases when policies about access control can be directly enforced by a device. The most common example of this is access control lists that are implemented by rewalls or routers in order to restrict the types of traf c that are allowed to pass through these devices in a network. Such policies are classi ed as con guration policies and not as access control policies, since no PDP is required to make decisions about the policies. Note that in this case, the access control actions are performed at the data plane (by a rewall or router) and not by a PDP at the management plane. 2.4.2.1 De nition of an Access Control Policy. A general form of an access control policy can be represented by the following:

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